Browse more than 70 science journal titles laser microirradiation of cells m w berns m kitzes k r strahs the light source is a dye laser pumped by the second and fourth harmonics of a yag laser the image of the investigated cell is projected on a video monitor and at the same time recorded on video tape some results are given of . Genome instability can lead to cell death senescence and cancerous transformation specific repair pathways have evolved to prevent accumulation of dna lesions studying these highly dynamic and specific repair pathways requires precise spatial and temporal resolution which can be achieved through a combination of laser microirradiaiton and live cell microscopy. A laser uv microbeam with a wavelength of 2573 a having a minimum spot diameter of approximately 05 mum was used to microirradiate interphase cells of a v 79 subline of chinese hamster cells. Search by keyword author year vol page advanced search hong kong university of science and technology clear water bay kowloon dna damage was introduced into sk n sh cells by laser microirradiation the cells were fixed within 5 min of introducing damage and then stained with an antibody recognizing polyadp ribose . New applications of laser microbeam irradiation to cell and developmental biology include a new instrument with a tunable wavelength 217 to 800 nanometer laser microbeam and a wide range of energies and exposure durations down to 25 x 10 12 second laser microbeams can be used for microirradiation of selected nucleolar genetic regions and for laser microdissection of mitotic and
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